Vitamin B4 Choline: full description, application, functions, dosage, sources.


Vitamin B4

Vitamin B4 or Choline is a thermostable amino alcohol, which takes an active part in the synthesis of lecithin, methionine, and also actively stimulates the synthesis of phospholipids and, accordingly, prevents fatty infiltration of the liver, stimulates the accumulation of glycogen in it.

Choline has a beneficial effect on the immunological reactions of the body, the synthesis of hemoglobin and is important for the formation of acetylcholine. The substance protects cell membranes from damage, normalizes cholesterol levels and has a calming effect. Under the influence of choline normalizes fat metabolism, prevents the formation of gallstones, improves metabolism in nerve tissues, reduces the total body weight.

Vitamin B4 is produced by beneficial intestinal bacteria in the human body and some is synthesized by the liver.

Through the introduction of vitamin b4 in food can be reduce pressure and improve short-term memory.

Need for choline

The Daily human need for vitamin B4 is 0.5 g. By diseases and various physical activities rate can reach 15-20 grams. Doctors recommend taking vitamin B4 during many hours or daily training in athletes, with the depletion of the nervous system and stress, with polyneuritis and lesions of the brain.

Vitamin Deficiency can be manifested in frequent nervous breakdowns, irritability, feeling of weakness and fatigue. Lack of substance in children under 5 years of age or in the diet of pregnant women can be negative affect the intellectual abilities of the child. 

Choline Functions:

  • has anti-sclerotic effect by lowering cholesterol;
  • reduces the degree of liver damage when hepatitis;
  • prevents diseases of the nervous system;
  • is a part of lecithin;
  • maintains a consistent state of the cell membrane;
  • takes part in the synthesis of acetylcholine, which is very important for the proper functioning of the nervous system as a whole.

Vitamin has a beneficial effect on the nervous tissue and brain. When a person concentrates, a special mechanism starts in the body – a sequence of biochemical reactions that result in the conversion of accumulated vitamin B4 into acetylcholine, a substance that is a conductor of nerve impulses.

Lack of vitamin B4 in the human body

Hypovitaminosis causes restrictions of vitamin B4 intake from food, folic acid and cyanocobalamin deficiency, nicotinic acid administration.

Choline Deficiency leads to:

  • inhibition of renal tubular apparatus;
  • delay in development and growth;
  • development of fatty liver infiltration.

Vitamin 4 is widely used in the treatment of diseases of the liver, vessels, heart, blood vessels, brain, hypothyroidism, diseases of the nervous system and in chronic alcoholism.

It is Important to know that vitamin b4 plays an important role in genital activity. The substance takes part in the formation of a hormone in the prostate gland, which is responsible for sperm motility.

It is Important to avoid the situation of complete absence of choline in the food consumed, as well as insufficient intake of the substance. People who suffer from chronic gastrointestinal diseases, have disorders in the absorption of nutrients, which affects the synthesis of vitamin b4. The risk group is the elderly, because they have significantly reduced the ability to assimilate choline, as well as disturbed the synthesis of this substance by the intestine.

Vitamin B4 Deficiency is characterized by impaired coordination, weakness in the legs, depression, development of dermatitis, pale mucous membranes.

Excess vitamin B4 in the human body

Choline in large doses has an extremely toxic effect on the human body, increasing intestinal peristalsis, inhibiting cardiac activity, reducing blood pressure and causing increased salivary secretion glands'.

Sources of vitamin B4

Choline contains sources of both animal and plant origin. Vitamin b4 is abundant in spinach, carrots, tomatoes, bran, cabbage, yeast, legumes, unrefined vegetable oils, cottage cheese, fish, kidneys, meat, liver, egg yolk, yarrow, plantain, dandelion, nettle, St. John's wort.

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